The first and only FDA-approved ophthalmic sealant for demonstrated wound leakage.
What is ReSure Sealant?
ReSure Sealant is a biocompatible hydrogel that creates a temporary, soft, and lubricious sealant to prevent fluid egress following cataract surgery.1,2
- Creates a watertight seal to minimize the risk of fluid outflow.1,2
- Softens over time, detaches, and is sloughed off in tears.2
- Conforms to the de-epithelialized tissue and adheres to surface irregularities.1
Patient and physician experience1*
- Patients reported similar comfort level scores compared to suture
- The majority of surgeons reported that it was “very easy” to use†
*A prospective, randomized, parallel-arm, controlled, multicenter, subject-masked study evaluated the safety and effectiveness of ReSure Sealant compared with a 10-0 nylon suture for preventing incision leakage from CCIs in patients having uneventful clear corneal cataract surgery after which a wound leak occurred. Patients scheduled for routine cataract surgery with no confounding ocular pathology were recruited. Patients were evaluated 1 hour after surgery and at 1, 3, 7, 14, 21, and 28 days. The primary endpoint was the percentage of eyes in which leakage occurred after treatment with ReSure Sealant or suture in the 7 days after surgery.1
†166 surgeons (54.8%) reported very easy to use.1
What are the benefits of ReSure Sealant?
- Eliminates the need for post-op follow-up visits for suture removal1
- Wound sealant in complex‡ or non-complex cataract cases1,3
- Eliminates potential complications related to suture1
‡In the pivotal trial, ReSure Sealant was not studied in complex cases.
How does ReSure Sealant work?
ReSure Sealant provides selective adherence to de-epithelialized tissue1
- Hydrogel selectively adheres to the surface irregularities of de-epithelialized tissue1
- Hydrogel typically persists for up to 1 to 3 days (up to 7 days in some cases) or until re-epithelialization occurs2
- As epithelium regenerates, surface irregularities necessary for sealant to stay on the eye disappear1
- Sealant sloughs off with tears, as it’s unable to adhere to re-epithelialized tissue1,2
Images courtesy of Deepinder K. Dhaliwal MD, LAc. University of Pittsburgh Medical Center
References: 1. Masket S, et al. J Cataract Refract Surg. 2014;40(12):2057-2066. 2. ReSure Sealant [instructions for use]. Bedford, MA: Ocular Therapeutix, Inc; LCN 80-1004-011 Rev D. 3. Nallasamy N, et al. J Cataract Refract Surg. 2017;43(8):1010-1014.